There is nothing particularly significant to note in the allotment given to Issachar. Their territory was in the north, in the region of Galilee. Most of the cities mentioned are not repeated elsewhere in the Bible. Their territory included the fertile Jezreel Valley which included the city of Jezreel.1
17 La quatrième part échut par le sort à Issacar, aux fils d'Issacar, selon leurs familles.