In context, for the Holy Spirit to be upon Simeon means that he was specially prepared to meet the Messiah. The Spirit revealed to him that he would meet the Messiah before his death, and the Spirit also providentially prompted Simeon to visit the temple on the same day that Jesus was there with his parents.
25 Et voici, il y avait à Jérusalem un homme appelé Siméon. Cet homme était juste et pieux, il attendait la consolation d'Israël, et l'Esprit-Saint était sur lui.