Lamentations 2:11 (ESV)

11 My eyes are spent with weeping; my stomach churns; my bile is poured out to the ground because of the destruction of the daughter of my people, because infants and babies faint in the streets of the city.

Now Jeremiah stops describing Jerusalem’s suffering. He describes his own suffering. He had often warned the parents of Jerusalem that they would lose their children, because they committed idolatry together with their children (Jeremiah 7:16–20; Jeremiah 9:21; Jeremiah 31:15). But now that he sees his prophesies fulfilled before his own eyes, his heart is broken.

In the first part of this verse Jeremiah literally says, “My eyes are at an end with tears, my bowels are fermenting; my liver is spilled out onto the ground.” He is completely overcome with grief.